Ontology highlight
ABSTRACT:
SUBMITTER: Doherty GJ
PROVIDER: S-EPMC3216663 | biostudies-literature | 2011 Nov
REPOSITORIES: biostudies-literature
Doherty Gary J GJ Åhlund Monika K MK Howes Mark T MT Morén Björn B Parton Robert G RG McMahon Harvey T HT Lundmark Richard R
Molecular biology of the cell 20110930 22
The rho GTPase-activating protein GTPase regulator associated with focal adhesion kinase-1 (GRAF1) remodels membranes into tubulovesicular clathrin-independent carriers (CLICs) mediating lipid-anchored receptor endocytosis. However, the cell biological functions of this highly prevalent endocytic pathway are unclear. In this article, we present biochemical and cell biological evidence that GRAF1 interacted with a network of endocytic and adhesion proteins and was found enriched at podosome-like ...[more]