Breast cancer susceptibility polymorphisms and endometrial cancer risk: a Collaborative Endometrial Cancer Study.
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ABSTRACT:
SUBMITTER: Healey CS
PROVIDER: S-EPMC3220608 | biostudies-literature | 2011 Dec
REPOSITORIES: biostudies-literature
Publications
Breast cancer susceptibility polymorphisms and endometrial cancer risk: a Collaborative Endometrial Cancer Study.
Healey Catherine S CS Ahmed Shahana S O'Mara Tracy A TA Ferguson Kaltin K Lambrechts Diether D Garcia-Dios Diego A DA Vergote Ignace I Amant Frederic F Howarth Kimberley K Gorman Maggie M Hodgson Shirley S Tomlinson Ian I Yang Hannah P HP Lissowska Jolanta J Brinton Louise A LA Chanock Stephen S Garcia-Closas Montserrat M Hall Per P Liu Jianjun J Shah Mitul M Pharoah Paul D P PD Thompson Deborah J DJ Rebbeck Timothy R TR Strom Brian L BL Dunning Alison M AM Easton Douglas F DF Spurdle Amanda B AB
Carcinogenesis 20110930 12
Recent large--scale association studies, both of genome-wide and candidate gene design, have revealed several single-nucleotide polymorphisms (SNPs) which are significantly associated with risk of developing breast cancer. As both breast and endometrial cancers are considered to be hormonally driven and share multiple risk factors, we investigated whether breast cancer risk alleles are also associated with endometrial cancer risk. We genotyped nine breast cancer risk SNPs in up to 4188 endometri ...[more]
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