Ontology highlight
ABSTRACT:
SUBMITTER: Rizzato C
PROVIDER: S-EPMC3220706 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Rizzato Cosmeri C Campa Daniele D Giese Nathalia N Werner Jens J Rachakonda P Sivaramakrishna PS Kumar Rajiv R Schanné Michaela M Greenhalf William W Costello Eithne E Khaw Kay-Tee KT Key Tim J TJ Siddiq Afshan A Lorenzo-Bermejo Justo J Burwinkel Barbara B Neoptolemos John P JP Büchler Markus W MW Hoheisel Jörg D JD Bauer Andrea A Canzian Federico F
PloS one 20111118 11
Pancreatic cancer has one of the worst mortality rates of all cancers. Little is known about its etiology, particularly regarding inherited risk. The PanScan project, a genome-wide association study, identified several common polymorphisms affecting pancreatic cancer susceptibility. Single nucleotide polymorphisms (SNPs) in ABO, sonic hedgehog (SHH), telomerase reverse transcriptase (TERT), nuclear receptor subfamily 5, group A, member 2 (NR5A2) were found to be associated with pancreatic cancer ...[more]