Ontology highlight
ABSTRACT:
SUBMITTER: Yasunaga T
PROVIDER: S-EPMC3223263 | biostudies-literature | 2011 Sep-Dec
REPOSITORIES: biostudies-literature
Yasunaga Takayuki T Itoh Keiji K Sokol Sergei Y SY
Mechanisms of development 20110806 7-10
The centrosome is essential for the formation of the cilia and has been implicated in cell polarization and signaling during early embryonic development. A number of Wnt pathway components were found to localize at the centrosome, but how this localization relates to their signaling functions is unclear. In this study, we assessed a role for Diversin, a putative Wnt pathway mediator, in developmental processes that involve cilia. We find that Diversin is specifically localized to the basal body ...[more]