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Structure of Golgi transport proteins.

ABSTRACT: The function of the Golgi has long been recognized to critically depend on vesicular transport from, to, and within its cisternae, involving constant membrane fission and fusion. These processes are mediated by Arf GTPases and coat proteins, and Rabs, tethers and SNARE proteins, respectively. In this article, we describe structural studies of Golgi coats and tethers and their interactions with SNAREs and GTPases as well as insights regarding membrane traffic processes that these have provided.

SUBMITTER: Kummel D

PROVIDER: S-EPMC3225946 | biostudies-literature | 2011 Dec

REPOSITORIES: biostudies-literature

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Structure of Golgi transport proteins.

Kümmel Daniel D Reinisch Karin M KM

Cold Spring Harbor perspectives in biology 20111201 12

The function of the Golgi has long been recognized to critically depend on vesicular transport from, to, and within its cisternae, involving constant membrane fission and fusion. These processes are mediated by Arf GTPases and coat proteins, and Rabs, tethers and SNARE proteins, respectively. In this article, we describe structural studies of Golgi coats and tethers and their interactions with SNAREs and GTPases as well as insights regarding membrane traffic processes that these have provided. ...[more]

PMID: 21813399

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