The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.
Ontology highlight
ABSTRACT:
SUBMITTER: International HIV Controllers Study
PROVIDER: S-EPMC3235490 | biostudies-literature | 2010 Dec
REPOSITORIES: biostudies-literature
Publications
The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.
Pereyra Florencia F Jia Xiaoming X McLaren Paul J PJ Telenti Amalio A de Bakker Paul I W PI Walker Bruce D BD Ripke Stephan S Brumme Chanson J CJ Pulit Sara L SL Carrington Mary M Kadie Carl M CM Carlson Jonathan M JM Heckerman David D Graham Robert R RR Plenge Robert M RM Deeks Steven G SG Gianniny Lauren L Crawford Gabriel G Sullivan Jordan J Gonzalez Elena E Davies Leela L Camargo Amy A Moore Jamie M JM Beattie Nicole N Gupta Supriya S Crenshaw Andrew A Burtt Noël P NP Guiducci Candace C Gupta Namrata N Gao Xiaojiang X Qi Ying Y Yuki Yuko Y Piechocka-Trocha Alicja A Cutrell Emily E Rosenberg Rachel R Moss Kristin L KL Lemay Paul P O'Leary Jessica J Schaefer Todd T Verma Pranshu P Toth Ildiko I Block Brian B Baker Brett B Rothchild Alissa A Lian Jeffrey J Proudfoot Jacqueline J Alvino Donna Marie L DM Vine Seanna S Addo Marylyn M MM Allen Todd M TM Altfeld Marcus M Henn Matthew R MR Le Gall Sylvie S Streeck Hendrik H Haas David W DW Kuritzkes Daniel R DR Robbins Gregory K GK Shafer Robert W RW Gulick Roy M RM Shikuma Cecilia M CM Haubrich Richard R Riddler Sharon S Sax Paul E PE Daar Eric S ES Ribaudo Heather J HJ Agan Brian B Agarwal Shanu S Ahern Richard L RL Allen Brady L BL Altidor Sherly S Altschuler Eric L EL Ambardar Sujata S Anastos Kathryn K Anderson Ben B Anderson Val V Andrady Ushan U Antoniskis Diana D Bangsberg David D Barbaro Daniel D Barrie William W Bartczak J J Barton Simon S Basden Patricia P Basgoz Nesli N Bazner Suzane S Bellos Nicholaos C NC Benson Anne M AM Berger Judith J Bernard Nicole F NF Bernard Annette M AM Birch Christopher C Bodner Stanley J SJ Bolan Robert K RK Boudreaux Emilie T ET Bradley Meg M Braun James F JF Brndjar Jon E JE Brown Stephen J SJ Brown Katherine K Brown Sheldon T ST Burack Jedidiah J Bush Larry M LM Cafaro Virginia V Campbell Omobolaji O Campbell John J Carlson Robert H RH Carmichael J Kevin JK Casey Kathleen K KK Cavacuiti Chris C Celestin Gregory G Chambers Steven T ST Chez Nancy N Chirch Lisa M LM Cimoch Paul J PJ Cohen Daniel D Cohn Lillian E LE Conway Brian B Cooper David A DA Cornelson Brian B Cox David T DT Cristofano Michael V MV Cuchural George G Czartoski Julie L JL Dahman Joseph M JM Daly Jennifer S JS Davis Benjamin T BT Davis Kristine K Davod Sheila M SM DeJesus Edwin E Dietz Craig A CA Dunham Eleanor E Dunn Michael E ME Ellerin Todd B TB Eron Joseph J JJ Fangman John J W JJ Farel Claire E CE Ferlazzo Helen H Fidler Sarah S Fleenor-Ford Anita A Frankel Renee R Freedberg Kenneth A KA French Neel K NK Fuchs Jonathan D JD Fuller Jon D JD Gaberman Jonna J Gallant Joel E JE Gandhi Rajesh T RT Garcia Efrain E Garmon Donald D Gathe Joseph C JC Gaultier Cyril R CR Gebre Wondwoosen W Gilman Frank D FD Gilson Ian I Goepfert Paul A PA Gottlieb Michael S MS Goulston Claudia C Groger Richard K RK Gurley T Douglas TD Haber Stuart S Hardwicke Robin R Hardy W David WD Harrigan P Richard PR Hawkins Trevor N TN Heath Sonya S Hecht Frederick M FM Henry W Keith WK Hladek Melissa M Hoffman Robert P RP Horton James M JM Hsu Ricky K RK Huhn Gregory D GD Hunt Peter P Hupert Mark J MJ Illeman Mark L ML Jaeger Hans H Jellinger Robert M RM John Mina M Johnson Jennifer A JA Johnson Kristin L KL Johnson Heather H Johnson Kay K Joly Jennifer J Jordan Wilbert C WC Kauffman Carol A CA Khanlou Homayoon H Killian Robert K RK Kim Arthur Y AY Kim David D DD Kinder Clifford A CA Kirchner Jeffrey T JT Kogelman Laura L Kojic Erna Milunka EM Korthuis P Todd PT Kurisu Wayne W Kwon Douglas S DS LaMar Melissa M Lampiris Harry H Lanzafame Massimiliano M Lederman Michael M MM Lee David M DM Lee Jean M L JM Lee Marah J MJ Lee Edward T Y ET Lemoine Janice J Levy Jay A JA Llibre Josep M JM Liguori Michael A MA Little Susan J SJ Liu Anne Y AY Lopez Alvaro J AJ Loutfy Mono R MR Loy Dawn D Mohammed Debbie Y DY Man Alan A Mansour Michael K MK Marconi Vincent C VC Markowitz Martin M Marques Rui R Martin Jeffrey N JN Martin Harold L HL Mayer Kenneth Hugh KH McElrath M Juliana MJ McGhee Theresa A TA McGovern Barbara H BH McGowan Katherine K McIntyre Dawn D Mcleod Gavin X GX Menezes Prema P Mesa Greg G Metroka Craig E CE Meyer-Olson Dirk D Miller Andy O AO Montgomery Kate K Mounzer Karam C KC Nagami Ellen H EH Nagin Iris I Nahass Ronald G RG Nelson Margret O MO Nielsen Craig C Norene David L DL O'Connor David H DH Ojikutu Bisola O BO Okulicz Jason J Oladehin Olakunle O OO Oldfield Edward C EC Olender Susan A SA Ostrowski Mario M Owen William F WF Pae Eunice E Parsonnet Jeffrey J Pavlatos Andrew M AM Perlmutter Aaron M AM Pierce Michael N MN Pincus Jonathan M JM Pisani Leandro L Price Lawrence Jay LJ Proia Laurie L Prokesch Richard C RC Pujet Heather Calderon HC Ramgopal Moti M Rathod Almas A Rausch Michael M Ravishankar J J Rhame Frank S FS Richards Constance Shamuyarira CS Richman Douglas D DD Rodes Berta B Rodriguez Milagros M Rose Richard C RC Rosenberg Eric S ES Rosenthal Daniel D Ross Polly E PE Rubin David S DS Rumbaugh Elease E Saenz Luis L Salvaggio Michelle R MR Sanchez William C WC Sanjana Veeraf M VM Santiago Steven S Schmidt Wolfgang W Schuitemaker Hanneke H Sestak Philip M PM Shalit Peter P Shay William W Shirvani Vivian N VN Silebi Vanessa I VI Sizemore James M JM Skolnik Paul R PR Sokol-Anderson Marcia M Sosman James M JM Stabile Paul P Stapleton Jack T JT Starrett Sheree S Stein Francine F Stellbrink Hans-Jurgen HJ Sterman F Lisa FL Stone Valerie E VE Stone David R DR Tambussi Giuseppe G Taplitz Randy A RA Tedaldi Ellen M EM Telenti Amalio A Theisen William W Torres Richard R Tosiello Lorraine L Tremblay Cecile C Tribble Marc A MA Trinh Phuong D PD Tsao Alice A Ueda Peggy P Vaccaro Anthony A Valadas Emilia E Vanig Thanes J TJ Vecino Isabel I Vega Vilma M VM Veikley Wenoah W Wade Barbara H BH Walworth Charles C Wanidworanun Chingchai C Ward Douglas J DJ Warner Daniel A DA Weber Robert D RD Webster Duncan D Weis Steve S Wheeler David A DA White David J DJ Wilkins Ed E Winston Alan A Wlodaver Clifford G CG van't Wout Angelique A Wright David P DP Yang Otto O OO Yurdin David L DL Zabukovic Brandon W BW Zachary Kimon C KC Zeeman Beth B Zhao Meng M
Science (New York, N.Y.) 20101104 6010
Infectious and inflammatory diseases have repeatedly shown strong genetic associations within the major histocompatibility complex (MHC); however, the basis for these associations remains elusive. To define host genetic effects on the outcome of a chronic viral infection, we performed genome-wide association analysis in a multiethnic cohort of HIV-1 controllers and progressors, and we analyzed the effects of individual amino acids within the classical human leukocyte antigen (HLA) proteins. We i ...[more]
