Ontology highlight
ABSTRACT:
SUBMITTER: Luchansky MS
PROVIDER: S-EPMC3241882 | biostudies-literature | 2011 Dec
REPOSITORIES: biostudies-literature
Luchansky Matthew S MS Bailey Ryan C RC
Journal of the American Chemical Society 20111122 50
We have developed a silicon photonic biosensing chip capable of multiplexed protein measurements in a biomolecularly complex cell culture matrix. Using this multiplexed platform combined with fast one-step sandwich immunoassays, we perform a variety of T cell cytokine secretion studies with excellent time-to-result. Using 32-element arrays of silicon photonic microring resonators, the cytokines interleukin-2 (IL-2), interleukin-4 (IL-4), interleukin-5 (IL-5), and tumor necrosis factor alpha (TNF ...[more]