Ontology highlight
ABSTRACT:
SUBMITTER: Tong J
PROVIDER: S-EPMC3251753 | biostudies-literature | 2012 Jan
REPOSITORIES: biostudies-literature
Tong Jing J Wang You-wei YW Lu Yuan-an YA
Journal of Zhejiang University. Science. B 20120101 1
Infection with hepatitis C virus (HCV) affects approximately 170 million people worldwide. However, no vaccine or immunoglobulin is currently available for the prevention of HCV infection. The standard of care (SOC) involving pegylated interferon-α (PEG-IFN α) plus ribavirin (RBV) for 48 weeks results in a sustained virologic response in less than 50% of patients with chronic hepatitis C genotype 1, the most prevalent type of HCV in North America and Europe. Recently, reliable in vitro culture s ...[more]