Ontology highlight
ABSTRACT:
SUBMITTER: Zhang H
PROVIDER: S-EPMC3253737 | biostudies-literature | 2011 Dec
REPOSITORIES: biostudies-literature
Zhang Huaping H Samadi Abbas K AK Gallagher Robert J RJ Araya Juan J JJ Tong Xiaoqin X Day Victor W VW Cohen Mark S MS Kindscher Kelly K Gollapudi Rao R Timmermann Barbara N BN
Journal of natural products 20111118 12
Fourteen new withanolides, 1-14, named withalongolides A-N, respectively, were isolated from the aerial parts of Physalis longifolia together with eight known compounds (15-22). The structures of compounds 1-14 were elucidated through spectroscopic techniques and chemical methods. In addition, the structures of withanolides 1, 2, 3, and 6 were confirmed by X-ray crystallographic analysis. Using a MTS viability assay, eight withanolides (1, 2, 3, 7, 8, 15, 16, and 19) and four acetylated derivati ...[more]