Ontology highlight
ABSTRACT:
SUBMITTER: Kalb SR
PROVIDER: S-EPMC3263758 | biostudies-literature | 2012 Jan
REPOSITORIES: biostudies-literature
FEBS letters 20111209 2
Botulinum neurotoxins (BoNTs) cause botulism by cleaving proteins necessary for nerve transmission. There are seven serotypes of BoNT, A-G, characterized by their response to antisera. Many serotypes are further distinguished into differing subtypes based on amino acid sequence, some of which result in functional differences. Our laboratory previously reported that all tested subtypes within each serotype have the same site of enzymatic activity. Recently, three new subtypes of BoNT/F; /F3, /F4, ...[more]