Ontology highlight
ABSTRACT:
SUBMITTER: Choi Y
PROVIDER: S-EPMC3271187 | biostudies-literature | 2012 Feb
REPOSITORIES: biostudies-literature
Journal of the American Chemical Society 20120124 4
The dynamic processivity of individual T4 lysozyme molecules was monitored in the presence of either linear or cross-linked peptidoglycan substrates. Single-molecule monitoring was accomplished using a novel electronic technique in which lysozyme molecules were tethered to single-walled carbon nanotube field-effect transistors through pyrene linker molecules. The substrate-driven hinge-bending motions of lysozyme induced dynamic electronic signals in the underlying transistor, allowing long-term ...[more]