Ontology highlight
ABSTRACT:
SUBMITTER: Predazzi IM
PROVIDER: S-EPMC3276570 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Predazzi Irene Marta IM Norata Giuseppe Danilo GD Vecchione Lucia L Garlaschelli Katia K Amati Francesca F Grigore Liliana L Cutuli Lucia L Pirillo Angela A Tramontana Simona S Romeo Francesco F Novelli Giuseppe G Catapano Alberico Luigi AL
PloS one 20120209 2
<h4>Background and purpose</h4>The lectin-like oxidised LDL receptor-1 (OLR1) gene encodes a scavenger receptor implicated in the pathogenesis of atherosclerosis. Although functional roles have been suggested for two variants, epidemiological studies on OLR1 have been inconsistent.<h4>Methods</h4>We tested the association between the non-synonymous substitution K167N (rs11053646) and intima media thickness of the common carotid artery (CCA-IMT) in 2,141 samples from the Progression of Lesions in ...[more]