Ontology highlight
ABSTRACT:
SUBMITTER: Eckelmann J
PROVIDER: S-EPMC3302070 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Eckelmann Jens J Saggiomo Vittorio V Fischmann Svenja S Lüning Ulrich U
Beilstein journal of organic chemistry 20120103
A bi-macrocycle with an incorporated isophthalamide substructure was synthesized by double amide formation between an isophthaloyl dichloride and two equivalents of a bis(alkenyloxy)aniline, followed by ring-closing metathesis and hydrogenation. In contrast to many related isophthalamides, the concave host exhibits a better binding for oxides, such as DMSO or pyridine-N-oxide, than for halide anions. A general method for a quick estimation of the strength of binding derived from only a few data ...[more]