Ontology highlight
ABSTRACT:
SUBMITTER: Cruz J
PROVIDER: S-EPMC3306807 | biostudies-literature | 2012 Feb
REPOSITORIES: biostudies-literature
Cruz Josefa J Mane-Padros Daniel D Zou Zhen Z Raikhel Alexander S AS
Molecular and cellular endocrinology 20111117 2
Mosquitoes are adapted to using vertebrate blood as a nutrient source to promote egg development and as a consequence serve as disease vectors. Blood-meal activated reproductive events in female mosquitoes are hormonally and nutritionally controlled with an insect steroid hormone 20-hydroxyecdysone (20E) playing a central role. The nuclear receptor E75 is an essential factor in the 20E genetic hierarchy, however functions of its three isoforms - E75A, E75B, and E75C - in mosquito reproduction ar ...[more]