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CytoSaddleSum: a functional enrichment analysis plugin for Cytoscape based on sum-of-weights scores.


ABSTRACT: CytoSaddleSum provides Cytoscape users with access to the functionality of SaddleSum, a functional enrichment tool based on sum-of-weight scores. It operates by querying SaddleSum locally (using the standalone version) or remotely (through an HTTP request to a web server). The functional enrichment results are shown as a term relationship network, where nodes represent terms and edges show term relationships. Furthermore, query results are written as Cytoscape attributes allowing easy saving, retrieval and integration into network-based data analysis workflows.

SUBMITTER: Stojmirovic A 

PROVIDER: S-EPMC3307116 | biostudies-literature | 2012 Mar

REPOSITORIES: biostudies-literature

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CytoSaddleSum: a functional enrichment analysis plugin for Cytoscape based on sum-of-weights scores.

Stojmirovic Aleksandar A   Bliskovsky Alexander A   Yu Yi-Kuo YK  

Bioinformatics (Oxford, England) 20120215 6


CytoSaddleSum provides Cytoscape users with access to the functionality of SaddleSum, a functional enrichment tool based on sum-of-weight scores. It operates by querying SaddleSum locally (using the standalone version) or remotely (through an HTTP request to a web server). The functional enrichment results are shown as a term relationship network, where nodes represent terms and edges show term relationships. Furthermore, query results are written as Cytoscape attributes allowing easy saving, re  ...[more]

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