Ontology highlight
ABSTRACT:
SUBMITTER: Tang B
PROVIDER: S-EPMC3651407 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Tang Biao B Wang Qi Q Yang Minjun M Xie Feng F Zhu Yongqiang Y Zhuo Ying Y Wang Shengyue S Gao Hong H Ding Xiaoming X Zhang Lixin L Zhao Guoping G Zheng Huajun H
BMC genomics 20130430
<h4>Background</h4>With the emergence of next-generation sequencing, the availability of prokaryotic genome sequences is expanding rapidly. A total of 5,276 genomes have been released since 2008, yet only 1,692 genomes were complete. The final phase of microbial genome sequencing, particularly gap closing, is frequently the rate-limiting step either because of complex genomic structures that cause sequence bias even with high genomic coverage, or the presence of repeat sequences that may cause g ...[more]