Kinetic schemes for post-synchronized single molecule dynamics.
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ABSTRACT:
SUBMITTER: Chen C
PROVIDER: S-EPMC3309285 | biostudies-literature | 2012 Mar
REPOSITORIES: biostudies-literature
Publications
Kinetic schemes for post-synchronized single molecule dynamics.
Chen Chunlai C Greenberg Michael J MJ Laakso Joseph M JM Ostap E Michael EM Goldman Yale E YE Shuman Henry H
Biophysical journal 20120320 6
Recordings from single molecule experiments can be aggregated to determine average kinetic properties of the system under observation. The kinetics after a synchronized reaction step can be interpreted using all of the standard tools developed for ensemble perturbation experiments. The kinetics leading up to a synchronized event, determined by the lifetimes of the preceding states; however, are not as obvious if the reaction has reversible steps or branches. Here we describe a general procedure ...[more]
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