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Divergent HIV and simian immunodeficiency virus surveillance, Zaire.

ABSTRACT: Recent HIV infection or divergent HIV or simian immunodeficiency virus (SIV) strains may be responsible for Western blot-indeterminate results on 70 serum samples from Zairian hospital employees that were reactive in an enzyme immunoassay. Using universal polymerase chain reaction HIV-1, HIV-2, and SIV primers, we detected 1 (1.4%) HIV-1 sequence. Except for 1 sample, no molecular evidence for unusual HIV- or SIV-like strains in this sampling was found.

SUBMITTER: Schaefer A

PROVIDER: S-EPMC3310624 | biostudies-literature | 2005 Sep

REPOSITORIES: biostudies-literature

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Divergent HIV and simian immunodeficiency virus surveillance, Zaire.

Schaefer Amanda A Robbins Kenneth E KE Nzilambi Eugene Nzila EN St Louis Michael E ME Quinn Thomas C TC Folks Thomas M TM Kalish Marcia L ML Pieniazek Danuta D

Emerging infectious diseases 20050901 9

Recent HIV infection or divergent HIV or simian immunodeficiency virus (SIV) strains may be responsible for Western blot-indeterminate results on 70 serum samples from Zairian hospital employees that were reactive in an enzyme immunoassay. Using universal polymerase chain reaction HIV-1, HIV-2, and SIV primers, we detected 1 (1.4%) HIV-1 sequence. Except for 1 sample, no molecular evidence for unusual HIV- or SIV-like strains in this sampling was found. ...[more]

PMID: 16229778

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