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Functionalized nanostructures with application in regenerative medicine.


ABSTRACT: In the last decade, both regenerative medicine and nanotechnology have been broadly developed leading important advances in biomedical research as well as in clinical practice. The manipulation on the molecular level and the use of several functionalized nanoscaled materials has application in various fields of regenerative medicine including tissue engineering, cell therapy, diagnosis and drug and gene delivery. The themes covered in this review include nanoparticle systems for tracking transplanted stem cells, self-assembling peptides, nanoparticles for gene delivery into stem cells and biomimetic scaffolds useful for 2D and 3D tissue cell cultures, transplantation and clinical application.

SUBMITTER: Peran M 

PROVIDER: S-EPMC3317746 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature

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Functionalized nanostructures with application in regenerative medicine.

Perán Macarena M   García María A MA   López-Ruiz Elena E   Bustamante Milán M   Jiménez Gema G   Madeddu Roberto R   Marchal Juan A JA  

International journal of molecular sciences 20120322 3


In the last decade, both regenerative medicine and nanotechnology have been broadly developed leading important advances in biomedical research as well as in clinical practice. The manipulation on the molecular level and the use of several functionalized nanoscaled materials has application in various fields of regenerative medicine including tissue engineering, cell therapy, diagnosis and drug and gene delivery. The themes covered in this review include nanoparticle systems for tracking transpl  ...[more]

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