Ontology highlight
ABSTRACT:
SUBMITTER: Masuda K
PROVIDER: S-EPMC3335050 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Masuda Katsuyoshi K Koizumi Ayako A Nakajima Ken-ichiro K Tanaka Takaharu T Abe Keiko K Misaka Takumi T Ishiguro Masaji M
PloS one 20120420 4
One of the most distinctive features of human sweet taste perception is its broad tuning to chemically diverse compounds ranging from low-molecular-weight sweeteners to sweet-tasting proteins. Many reports suggest that the human sweet taste receptor (hT1R2-hT1R3), a heteromeric complex composed of T1R2 and T1R3 subunits belonging to the class C G protein-coupled receptor family, has multiple binding sites for these sweeteners. However, it remains unclear how the same receptor recognizes such div ...[more]