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5-Bromo-N-(3,4-dimeth-oxy-benz-yl)pyridin-2-amine.

ABSTRACT: The title compound, C(14)H(15)BrN(2)O(2), an inter-mediate in drug discovery, was synthesized by the reaction of 5-bromo-pyridin-2-amine and 3,4-dimeth-oxy-benzaldehyde. In the crystal, molecules are linked via pairs ofN-H?N hydrogen bonds, leading to the formation of inversion dimers. A short contact occurs between the aryl H atom (ortho position from N) and the centroid of the benzene ring.

SUBMITTER: Li J

PROVIDER: S-EPMC3344531 | biostudies-literature | 2012 May

REPOSITORIES: biostudies-literature

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5-Bromo-N-(3,4-dimeth-oxy-benz-yl)pyridin-2-amine.

Li Jie J Lu Lin-Yan LY Shen Wang-Xing WX Shi Jian-You JY

Acta crystallographica. Section E, Structure reports online 20120418 Pt 5

The title compound, C(14)H(15)BrN(2)O(2), an inter-mediate in drug discovery, was synthesized by the reaction of 5-bromo-pyridin-2-amine and 3,4-dimeth-oxy-benzaldehyde. In the crystal, molecules are linked via pairs ofN-H⋯N hydrogen bonds, leading to the formation of inversion dimers. A short contact occurs between the aryl H atom (ortho position from N) and the centroid of the benzene ring. ...[more]

PMID: 22590293

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