Ontology highlight
ABSTRACT:
SUBMITTER: Kodama K
PROVIDER: S-EPMC3344989 | biostudies-literature | 2012 May
REPOSITORIES: biostudies-literature
Proceedings of the National Academy of Sciences of the United States of America 20120412 18
Type 2 diabetes (T2D) is a complex, polygenic disease affecting nearly 300 million people worldwide. T2D is primarily characterized by insulin resistance, and growing evidence has indicated the causative link between adipose tissue inflammation and the development of insulin resistance. Genetic association studies have successfully revealed a number of important genes consistently associated with T2D to date. However, these robust T2D-associated genes do not fully elucidate the mechanisms underl ...[more]