Pd(II)-catalyzed para-selective C-H arylation of monosubstituted arenes.

ABSTRACT: Pd-catalyzed highly para-selective C-H arylation of monosubstituted arenes (including toluene) is developed for the first time using an F(+) reagent as a bystanding oxidant. This finding provides a new retrosynthetic disconnection for para-substituted biaryl synthesis via C-H/C-H cross-coupling.

SUBMITTER: Wang X 

PROVIDER: S-EPMC3345815 | biostudies-literature | 2011 Sep

REPOSITORIES: biostudies-literature