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Pd(II)-Catalyzed C3-Selective Arylation of Pyridine with (Hetero)arenes.

ABSTRACT: Palladium catalyzed, nondirected C3-selective arylation of pyridines with arenes and heteroarenes in the presence of 1,10-phenanthroline as the ligand has been developed. The optimized conditions allow for a highly C3-selective arylation of pyridines, affording various 3,3'-bipyridines and 3-arylpyridines.

SUBMITTER: Gao GL

PROVIDER: S-EPMC4821414 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature

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Pd(II)-Catalyzed C3-Selective Arylation of Pyridine with (Hetero)arenes.

Gao Guo-Lin GL Xia Wujiong W Jain Pankaj P Yu Jin-Quan JQ

Organic letters 20160202 4

Palladium catalyzed, nondirected C3-selective arylation of pyridines with arenes and heteroarenes in the presence of 1,10-phenanthroline as the ligand has been developed. The optimized conditions allow for a highly C3-selective arylation of pyridines, affording various 3,3'-bipyridines and 3-arylpyridines. ...[more]

PMID: 26835845

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