Ontology highlight
ABSTRACT:
SUBMITTER: Shirazi HA
PROVIDER: S-EPMC3356104 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Shirazi Haider A HA Grimm Sean S Raizer Jeffrey J Mehta Minesh P MP
Frontiers in oncology 20111028
Over the past two decades, management of newly diagnosed glioblastoma has undergone significant evolution. While surgery has long been a mainstay of management for this disease, and while radiotherapy has a proven survival role, initial efforts at radiotherapy dose escalation, use of radiosurgery, brachytherapy, and altered fractionation did not improve patient survival. Recently, multiple modality therapy integrating maximal safe resection, postoperative radiation, and new systemic therapies ha ...[more]