Ontology highlight
ABSTRACT:
SUBMITTER: Hottinger AF
PROVIDER: S-EPMC3905088 | biostudies-literature | 2014 Jan
REPOSITORIES: biostudies-literature
Hottinger Andreas F AF Stupp Roger R Homicsko Krisztian K
Chinese journal of cancer 20140101 1
Glioblastoma multiforme (GBM) is the most common malignant primary brain tumor in adults. Standard therapeutic approaches provide modest improvement in the progression-free and overall survival, necessitating the investigation of novel therapies. We review the standard treatment options for GBM and evaluate the results obtained in clinical trials for promising novel approaches, including the inhibition of angiogenesis, targeted approaches against molecular pathways, immunotherapies, and local tr ...[more]