Ontology highlight
ABSTRACT:
SUBMITTER: Pan M
PROVIDER: S-EPMC3357521 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Pan Mingjie M Wang Xingsheng X Liao Jianmin J Yin Dengke D Li Suqin S Pan Ying Y Wang Yao Y Xie Guangyan G Zhang Shumin S Li Yuexi Y
Clinical & developmental immunology 20120509
Twenty B candidate epitopes of glycoproteins B (gB2), C (gC2), E (gE2), G (gG2), and I (gI2) of herpes simplex virus type 2 (HSV-2) were predicted using DNAstar, Biosun, and Antheprot methods combined with the polynomial method. Subsequently, the biological functions of the peptides were tested via experiments in vitro. Among the 20 epitope peptides, 17 could react with the antisera to the corresponding parent proteins in the EIA tests. In particular, five peptides, namely, gB2(466-473) (EQDRKPR ...[more]