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A general, enantioselective synthesis of protected morpholines and piperazines.


ABSTRACT: A short, high yielding protocol has been developed for the enantioselective and general synthesis of C2-functionalized, benzyl protected morpholines and orthogonally N,N'-protected piperazines from a common intermediate.

SUBMITTER: O'Reilly MC 

PROVIDER: S-EPMC3369273 | biostudies-literature | 2012 Jun

REPOSITORIES: biostudies-literature

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A general, enantioselective synthesis of protected morpholines and piperazines.

O'Reilly Matthew C MC   Lindsley Craig W CW  

Organic letters 20120522 11


A short, high yielding protocol has been developed for the enantioselective and general synthesis of C2-functionalized, benzyl protected morpholines and orthogonally N,N'-protected piperazines from a common intermediate. ...[more]

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