Ontology highlight
ABSTRACT:
SUBMITTER: Rosu-Myles M
PROVIDER: S-EPMC3374805 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Rosu-Myles Michael M She Yi-Min YM Fair Joel J Muradia Gauri G Mehic Jelica J Menendez Pablo P Prasad Shiv S SS Cyr Terry D TD
PloS one 20120613 6
Bone marrow stromal cell cultures contain multipotent cells that may have therapeutic utility for tissue restoration; however, the identity of the cell that maintains this function remains poorly characterized. We have utilized a unique model of murine bone marrow stroma in combination with liquid chromatography mass spectrometry to compare the nuclear, cytoplasmic and membrane associated proteomes of multipotent (MSC) (CD105+) and non-multipotent (CD105-) stromal cells. Among the 25 most reliab ...[more]