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1-{[(2,3-Dihydro-1H-inden-2-yl)-oxy]meth-yl}quinazoline-2,4(1H,3H)-dione.

ABSTRACT: In the title mol-ecule, C(18)H(16)N(2)O(3), the five-membered ring has an envelope conformation, with the substituted C atom deviating by 0.342?(4)?Å from the mean plane P calculated for the remainder of the non-H atoms of the 2,3-dihydro-1H-indene fragment. The mean planes of quinazoline-2,4(1H,3H)-dione fragment and P form a dihedral angle of 59.08?(4)°. In the crystal, pairs of N-H?O hydrogen bonds link mol-ecules into inversion dimers, and weak C-H?O hydrogen bonds and ?-? inter-actions between the benzene rings of the quinazoline ring systems [centroid-centroid distance = 3.538?(3)?Å] further consolidate the packing.

SUBMITTER: El-Brollosy NR

PROVIDER: S-EPMC3379431 | biostudies-literature | 2012 Jun

REPOSITORIES: biostudies-literature

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1-{[(2,3-Dihydro-1H-inden-2-yl)-oxy]meth-yl}quinazoline-2,4(1H,3H)-dione.

El-Brollosy Nasser R NR Dege Necmi N Demirtaş Güneş G Attia Mohamed I MI El-Emam Ali A AA Büyükgüngör Orhan O

Acta crystallographica. Section E, Structure reports online 20120523 Pt 6

In the title mol-ecule, C(18)H(16)N(2)O(3), the five-membered ring has an envelope conformation, with the substituted C atom deviating by 0.342 (4) Å from the mean plane P calculated for the remainder of the non-H atoms of the 2,3-dihydro-1H-indene fragment. The mean planes of quinazoline-2,4(1H,3H)-dione fragment and P form a dihedral angle of 59.08 (4)°. In the crystal, pairs of N-H⋯O hydrogen bonds link mol-ecules into inversion dimers, and weak C-H⋯O hydrogen bonds and π-π inter-actions betw ...[more]

PMID: 22719629

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