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Palladium-catalyzed C3-benzylation of indoles.

ABSTRACT: A general method for regioselective C3-benzylation of indoles has been developed. Various 3-substituted indoles and benzyl methyl carbonates with different electronic properties react under mild conditions to afford a diverse range of 3-benzylindolenine products in good yields.

SUBMITTER: Zhu Y 

PROVIDER: S-EPMC3383063 | biostudies-literature | 2012 Jan

REPOSITORIES: biostudies-literature

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Palladium-catalyzed C3-benzylation of indoles.

Zhu Ye Y   Rawal Viresh H VH  

Journal of the American Chemical Society 20111209 1

A general method for regioselective C3-benzylation of indoles has been developed. Various 3-substituted indoles and benzyl methyl carbonates with different electronic properties react under mild conditions to afford a diverse range of 3-benzylindolenine products in good yields. ...[more]

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