Ontology highlight
ABSTRACT:
SUBMITTER: Norberg O
PROVIDER: S-EPMC3405975 | biostudies-literature | 2012 Apr
REPOSITORIES: biostudies-literature
Norberg Oscar O Lee Irene H IH Aastrup Teodor T Yan Mingdi M Ramström Olof O
Biosensors & bioelectronics 20120128 1
The photoinitiated radical reactions between thiols and alkenes/alkynes (thiol-ene and thiol-yne chemistry) have been applied to a functionalization methodology to produce carbohydrate-presenting surfaces for analyses of biomolecular interactions. Polymer-coated quartz surfaces were functionalized with alkenes or alkynes in a straightforward photochemical procedure utilizing perfluorophenylazide (PFPA) chemistry. The alkene/alkyne surfaces were subsequently allowed to react with carbohydrate thi ...[more]