Ontology highlight
ABSTRACT:
SUBMITTER: Lu S
PROVIDER: S-EPMC9411599 | biostudies-literature | 2022 Aug
REPOSITORIES: biostudies-literature
Lü Shiwei S Wang Zipeng Z Zhu Shifa S
Nature communications 20220825 1
Macrocycles have fascinated scientists for over half a century due to their aesthetically appealing structures and broad utilities in chemical, material, and biological research. However, the efficient preparation of macrocycles remains an ongoing research challenge in organic synthesis because of the high entropic penalty involved in the ring-closing process. Herein we report a photocatalyzed thiol-yne click reaction to forge diverse sulfur-containing macrocycles (up to 35-membered ring) and li ...[more]