Ontology highlight
ABSTRACT:
SUBMITTER: Liu Q
PROVIDER: S-EPMC3412788 | biostudies-literature | 2012 Aug
REPOSITORIES: biostudies-literature
Liu Qiao Q Wang Hong H Liu Huihui H Teng Maikun M Li Xu X
Acta crystallographica. Section F, Structural biology and crystallization communications 20120731 Pt 8
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is an important enzyme in the glycolytic pathway. In addition to its conventional metabolic role, GAPDH has been identified to possess diverse cellular functions. In this study, glyceraldehyde-3-phosphate dehydrogenase 3, the third isoform of GAPDH from Saccharomyces cerevisiae, was cloned, expressed, purified and crystallized. The crystals belonged to space group I4(1)22, with unit-cell parameters a = b = 116.13, c = 119.21 Å. X-ray diffraction d ...[more]