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Molecular typing of Mycobacterium abscessus based on tandem-repeat polymorphism.

ABSTRACT: A variable-number tandem-repeat (VNTR) typing assay for the differentiation of Mycobacterium abscessus strains was developed. This assay showed complete reproducibility, locus stability, and a discriminatory power (Hunter-Gaston discriminatory index [HGDI] of 0.9563) that is superior to that of multilocus sequencing. It is a promising tool for the investigation of Mycobacterium abscessus epidemiology and nosocomial outbreaks.

SUBMITTER: Wong YL

PROVIDER: S-EPMC3421802 | biostudies-literature | 2012 Sep

REPOSITORIES: biostudies-literature

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Molecular typing of Mycobacterium abscessus based on tandem-repeat polymorphism.

Wong Y L YL Ong C S CS Ngeow Y F YF

Journal of clinical microbiology 20120703 9

A variable-number tandem-repeat (VNTR) typing assay for the differentiation of Mycobacterium abscessus strains was developed. This assay showed complete reproducibility, locus stability, and a discriminatory power (Hunter-Gaston discriminatory index [HGDI] of 0.9563) that is superior to that of multilocus sequencing. It is a promising tool for the investigation of Mycobacterium abscessus epidemiology and nosocomial outbreaks. ...[more]

PMID: 22760048

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