Ontology highlight
ABSTRACT:
SUBMITTER: Williamson KS
PROVIDER: S-EPMC3422551 | biostudies-literature | 2012 Aug
REPOSITORIES: biostudies-literature
Journal of the American Chemical Society 20120723 30
The regioselective and enantioselective oxyamination of alkenes with N-sulfonyl oxaziridines is catalyzed by a novel iron(II) bis(oxazoline) complex. This process affords oxazolidine products that can be easily manipulated to yield highly enantioenriched free amino alcohols. The regioselectivity of this process is complementary to that obtained from the analogous copper(II)-catalyzed reaction. Thus, both regioisomers of enantioenriched 1,2-aminoalcohols can be obtained using oxaziridine-mediated ...[more]