Ontology highlight
ABSTRACT:
SUBMITTER: Jackson LP
PROVIDER: S-EPMC3425711 | biostudies-literature | 2012 Aug
REPOSITORIES: biostudies-literature
Jackson Lauren P LP Kümmel Daniel D Reinisch Karin M KM Owen David J DJ
Current opinion in cell biology 20120622 4
Eukaryotic cells face a logistical challenge in ensuring prompt and precise delivery of vesicular cargo to specific organelles within the cell. Coat protein complexes select cargo and initiate vesicle formation, while multisubunit tethering complexes participate in the delivery of vesicles to target membranes. Understanding these macromolecular assemblies has greatly benefited from their structural characterization. Recent structural data highlight principles in coat recruitment and uncoating in ...[more]