Ontology highlight
ABSTRACT:
SUBMITTER: Galvagni F
PROVIDER: S-EPMC3426669 | biostudies-literature | 2012 Sep
REPOSITORIES: biostudies-literature
Galvagni Federico F Baldari Cosima Tatiana CT Oliviero Salvatore S Orlandini Maurizio M
Histochemistry and cell biology 20120529 3
One of the most important questions in cell biology concerns how cells reorganize after sensing polarity cues. In the present study, we describe the formation of an actin-rich domain on the apical surface of human primary endothelial cells adhering to the substrate and investigate its role in cell polarity. We used confocal immunofluorescence procedures to follow the redistribution of proteins required for endothelial cell polarity during spreading initiation. Activated Moesin, vascular endothel ...[more]