Ontology highlight
ABSTRACT:
SUBMITTER: Stranahan AM
PROVIDER: S-EPMC3427989 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Stranahan Alexis M AM Martin Bronwen B Chadwick Wayne W Park Sung-Soo SS Wang Liyun L Becker Kevin G KG Woodiii William H WH Zhang Yongqing Y Maudsley Stuart S
International journal of endocrinology 20120827
The hypothalamus is an essential relay in the neural circuitry underlying energy metabolism that needs to continually adapt to changes in the energetic environment. The neuroendocrine control of food intake and energy expenditure is associated with, and likely dependent upon, hypothalamic plasticity. Severe disturbances in energy metabolism, such as those that occur in obesity, are therefore likely to be associated with disruption of hypothalamic transcriptomic plasticity. In this paper, we inve ...[more]