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Oxidative condensations to form benzimidazole-substituted potassium organotrifluoroborates.

ABSTRACT: A library of benzimidazole-substituted potassium organotrifluoroborates was prepared via the condensation of various potassium formyl-substituted aryl- and heteroaryltrifluoroborates with aromatic 1,2-diamines under oxidative conditions. The efficient Suzuki-Miyaura cross-coupling of products thus formed to various aryl and heteroaryl bromides was achieved in good yields. The method allows the facile preparation of benzimidazole-containing triaromatic products in two steps from simple potassium formyl substituted aryl- or heteroaryltrifluoroborates.

SUBMITTER: Molander GA

PROVIDER: S-EPMC3428750 | biostudies-literature | 2012 Aug

REPOSITORIES: biostudies-literature

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Oxidative condensations to form benzimidazole-substituted potassium organotrifluoroborates.

Molander Gary A GA Ajayi Kehinde K

Organic letters 20120808 16

A library of benzimidazole-substituted potassium organotrifluoroborates was prepared via the condensation of various potassium formyl-substituted aryl- and heteroaryltrifluoroborates with aromatic 1,2-diamines under oxidative conditions. The efficient Suzuki-Miyaura cross-coupling of products thus formed to various aryl and heteroaryl bromides was achieved in good yields. The method allows the facile preparation of benzimidazole-containing triaromatic products in two steps from simple potassium ...[more]

PMID: 22873832

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