Androgen receptor CAG repeat polymorphism in males of six non-human primate species.
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ABSTRACT:
SUBMITTER: Mubiru JN
PROVIDER: S-EPMC3479659 | biostudies-literature | 2012 Feb
REPOSITORIES: biostudies-literature
Publications
Androgen receptor CAG repeat polymorphism in males of six non-human primate species.
Mubiru James N JN Cavazos Nicole N Hemmat Peggah P Garcia-Forey Magdalena M Shade Robert E RE Rogers Jeffrey J
Journal of medical primatology 20111007 1
<h4>Background</h4>Androgen receptor [CAG](n) microsatellite has been linked to human diseases.<h4>Methods</h4>Six non-human primates were genotyped for the [CAG](n) microsatellite.<h4>Results</h4>Marmosets and macaques are monomorphic, while mangabeys, baboons, and chimpanzees are polymorphic.<h4>Conclusions</h4>Non-human primates that are polymorphic for the microsatellite are candidate animal models for CAG-related diseases. ...[more]
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