Ontology highlight
ABSTRACT:
SUBMITTER: Karasavvas N
PROVIDER: S-EPMC3484815 | biostudies-literature | 2012 Nov
REPOSITORIES: biostudies-literature
Karasavvas Nicos N Billings Erik E Rao Mangala M Williams Constance C Zolla-Pazner Susan S Bailer Robert T RT Koup Richard A RA Madnote Sirinan S Arworn Duangnapa D Shen Xiaoying X Tomaras Georgia D GD Currier Jeffrey R JR Jiang Mike M Magaret Craig C Andrews Charla C Gottardo Raphael R Gilbert Peter P Cardozo Timothy J TJ Rerks-Ngarm Supachai S Nitayaphan Sorachai S Pitisuttithum Punnee P Kaewkungwal Jaranit J Paris Robert R Greene Kelli K Gao Hongmei H Gurunathan Sanjay S Tartaglia Jim J Sinangil Faruk F Korber Bette T BT Montefiori David C DC Mascola John R JR Robb Merlin L ML Haynes Barton F BF Ngauy Viseth V Michael Nelson L NL Kim Jerome H JH de Souza Mark S MS
AIDS research and human retroviruses 20121004 11
The Thai Phase III clinical trial (RV144) showed modest efficacy in preventing HIV-1 acquisition. Plasma collected from HIV-1-uninfected trial participants completing all injections with ALVAC-HIV (vCP1521) prime and AIDSVAX B/E boost were tested for antibody responses against HIV-1 gp120 envelope (Env). Peptide microarray analysis from six HIV-1 subtypes and group M consensus showed that vaccination induced antibody responses to the second variable (V2) loop of gp120 of multiple subtypes. We fu ...[more]