Ontology highlight
ABSTRACT:
SUBMITTER: He S
PROVIDER: S-EPMC3494591 | biostudies-literature | 2012 Nov
REPOSITORIES: biostudies-literature
He Shuyu S Wang Chaodong C Dong Haiyan H Xia Fucan F Zhou Hao H Jiang Xiaoshu X Pei Chunying C Ren Huan H Li Huashun H Li Rui R Xu Hongwei H
Autophagy 20120809 11
Autophagy is an important cellular recycling mechanism through self-digestion in responses to cellular stress such as starvation. Studies have shown that autophagy is involved in maintaining the homeostasis of the neural system during stroke. However, molecular mechanisms underlying neuronal autophagy in ischemic stroke remain poorly understood. Previously, we and others have shown that immune-related GTPase M (IRGM; termed IRGM1 in the mouse nomenclature) can regulate the survival of immune cel ...[more]