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Complete genome sequence analysis of a Newcastle disease virus isolated from a wild egret.


ABSTRACT: We report here the complete genomic sequence of a novel Newcastle disease virus (NDV) strain, egret/China/Guangxi/2011, isolated from an egret in Guangxi Province, southern China. A phylogenetic analysis based on a fusion gene comparison with different NDV strains revealed that egret/China/Guangxi/2011 was phylogenetically close to genotype VIIa NDV, and the deduced amino acid sequence was (112)R-R-R-K-R-F(117) at the fusion protein cleavage site. The whole nucleotide sequence had the highest homology (93.3%) with the sequence of strain chicken/Sukorejo/019/10 (GenBank accession number HQ697255). This study will help us to understand the epidemiology and molecular characteristics of Newcastle disease virus in a migratory egret.

SUBMITTER: Xie Z 

PROVIDER: S-EPMC3503033 | biostudies-literature | 2012 Dec

REPOSITORIES: biostudies-literature

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Complete genome sequence analysis of a Newcastle disease virus isolated from a wild egret.

Xie Zhixun Z   Xie Liji L   Chen Anli A   Liu Jiabo J   Pang Yaoshan Y   Deng Xianwen X   Xie Zhiqin Z   Fan Qing Q  

Journal of virology 20121201 24


We report here the complete genomic sequence of a novel Newcastle disease virus (NDV) strain, egret/China/Guangxi/2011, isolated from an egret in Guangxi Province, southern China. A phylogenetic analysis based on a fusion gene comparison with different NDV strains revealed that egret/China/Guangxi/2011 was phylogenetically close to genotype VIIa NDV, and the deduced amino acid sequence was (112)R-R-R-K-R-F(117) at the fusion protein cleavage site. The whole nucleotide sequence had the highest ho  ...[more]

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