Ontology highlight
ABSTRACT:
SUBMITTER: Rao Z
PROVIDER: S-EPMC3503665 | biostudies-literature | 2012 Dec
REPOSITORIES: biostudies-literature
The ubiquitin-proteasome pathway is a common cellular process in eukaryotic tissue. Ubiquitin binds to proteins and tags them for destruction; this tagging directs proteins to the proteosome in the cell that degrades and recycles unneeded proteins. The ubiquitin-proteasome pathway plays an important role in the regulation of cellular proteins with respect to cell cycle control, transcription, apoptosis, cell adhesion, angiogenesis, and tumour growth. This review article discusses the various way ...[more]