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Rh(III)-catalyzed directed C-H bond amidation of ferrocenes with isocyanates.

ABSTRACT: [RhCp*(OAc)(2)(H(2)O)] [Cp* = pentamethylcyclopentadienyl] catalyzed the C-H bond amidation of ferrocenes possessing directing groups with isocyanates in the presence of 2 equiv/Rh of HBF(4)·OEt(2). A variety of disubstituted ferrocenes were prepared in high yields, or excellent diastereoselectivities.

SUBMITTER: Takebayashi S

PROVIDER: S-EPMC3511021 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature

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Rh(III)-catalyzed directed C-H bond amidation of ferrocenes with isocyanates.

Takebayashi Satoshi S Shizuno Tsubasa T Otani Takashi T Shibata Takanori T

Beilstein journal of organic chemistry 20121029

[RhCp*(OAc)(2)(H(2)O)] [Cp* = pentamethylcyclopentadienyl] catalyzed the C-H bond amidation of ferrocenes possessing directing groups with isocyanates in the presence of 2 equiv/Rh of HBF(4)·OEt(2). A variety of disubstituted ferrocenes were prepared in high yields, or excellent diastereoselectivities. ...[more]

PMID: 23209521

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