Ontology highlight
ABSTRACT:
SUBMITTER: Semova I
PROVIDER: S-EPMC3517662 | biostudies-literature | 2012 Sep
REPOSITORIES: biostudies-literature
Semova Ivana I Carten Juliana D JD Stombaugh Jesse J Mackey Lantz C LC Knight Rob R Farber Steven A SA Rawls John F JF
Cell host & microbe 20120901 3
Regulation of intestinal dietary fat absorption is critical to maintaining energy balance. While intestinal microbiota clearly impact the host's energy balance, their role in intestinal absorption and extraintestinal metabolism of dietary fat is less clear. Using in vivo imaging of fluorescent fatty acid (FA) analogs delivered to gnotobiotic zebrafish hosts, we reveal that microbiota stimulate FA uptake and lipid droplet (LD) formation in the intestinal epithelium and liver. Microbiota increase ...[more]