Ontology highlight
ABSTRACT:
SUBMITTER: Houston I
PROVIDER: S-EPMC3521991 | biostudies-literature | 2013 Jan
REPOSITORIES: biostudies-literature
Houston Isaac I Peter Cyril J CJ Mitchell Amanda A Straubhaar Juerg J Rogaev Evgeny E Akbarian Schahram S
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20120530 1
Many cellular constituents in the human brain permanently exit from the cell cycle during pre- or early postnatal development, but little is known about epigenetic regulation of neuronal and glial epigenomes during maturation and aging, including changes in mood and psychosis spectrum disorders and other cognitive or emotional disease. Here, we summarize the current knowledge base as it pertains to genome organization in the human brain, including the regulation of DNA cytosine methylation and h ...[more]