Ontology highlight
ABSTRACT:
SUBMITTER: Koutsioumpa M
PROVIDER: S-EPMC3537032 | biostudies-literature | 2013 Jan
REPOSITORIES: biostudies-literature
Koutsioumpa Marina M Polytarchou Christos C Courty José J Zhang Yue Y Kieffer Nelly N Mikelis Constantinos C Skandalis Spyros S SS Hellman Ulf U Iliopoulos Dimitrios D Papadimitriou Evangelia E
The Journal of biological chemistry 20121116 1
The multifunctional protein nucleolin (NCL) is overexpressed on the surface of activated endothelial and tumor cells and mediates the stimulatory actions of several angiogenic growth factors, such as pleiotrophin (PTN). Because α(v)β(3) integrin is also required for PTN-induced cell migration, the aim of the present work was to study the interplay between NCL and α(v)β(3) by using biochemical, immunofluorescence, and proximity ligation assays in cells with genetically altered expression of the s ...[more]