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Solid immersion facilitates fluorescence microscopy with nanometer resolution and sub-angstrom emitter localization.

ABSTRACT: Exploring the maximum spatial resolution achievable in far-field optical imaging, we show that applying solid immersion lenses (SIL) in stimulated emission depletion (STED) microscopy addresses single spins with a resolution down to 2.4 ± 0.3 nm and with a localization precision of 0.09 nm.

SUBMITTER: Wildanger D

PROVIDER: S-EPMC3546393 | biostudies-literature | 2012 Nov

REPOSITORIES: biostudies-literature

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Solid immersion facilitates fluorescence microscopy with nanometer resolution and sub-ångström emitter localization.

Wildanger Dominik D Patton Brian R BR Schill Heiko H Marseglia Luca L Hadden J P JP Knauer Sebastian S Schönle Andreas A Rarity John G JG O'Brien Jeremy L JL Hell Stefan W SW Smith Jason M JM

Advanced materials (Deerfield Beach, Fla.) 20120912 44

Exploring the maximum spatial resolution achievable in far-field optical imaging, we show that applying solid immersion lenses (SIL) in stimulated emission depletion (STED) microscopy addresses single spins with a resolution down to 2.4 ± 0.3 nm and with a localization precision of 0.09 nm. ...[more]

PMID: 22968917

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